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clinical-grade imsc product cyp001 tm  (Cynata Therapeutics)

 
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    Cynata Therapeutics clinical-grade imsc product cyp001 tm
    Clinical Grade Imsc Product Cyp001 Tm, supplied by Cynata Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/imscs/cyp+001/pmc11794695-352-27-35
    Average 90 stars, based on 1 article reviews
    clinical-grade imsc product cyp001 tm - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    other:

    Article Title: Recent Advances in Extracellular Vesicle-Based Therapies Using Induced Pluripotent Stem Cell-Derived Mesenchymal Stromal Cells
    Article Snippet: A third clinical trial was recently announced, but not yet registered, sponsored by the University of Sydney using Cynata’s iMSCs, which will evaluate the effects of iMSCs in osteoarthritis in a phase III study ( https://files.cynata.com/629/201111Phase3OsteoarthritisClinicalTrialCommences.pdf ) (accessed on 13 September 2022).

    Clinical Proteomics:

    Article Title: Recent Advances in Extracellular Vesicle-Based Therapies Using Induced Pluripotent Stem Cell-Derived Mesenchymal Stromal Cells
    Article Snippet: .. Up to now, there are two registered clinical trials testing iMSCs, both designed by Cynata Therapeutics and using iMSCs produced by the patented CymerusTM platform technology. ..

    Produced:

    Article Title: Recent Advances in Extracellular Vesicle-Based Therapies Using Induced Pluripotent Stem Cell-Derived Mesenchymal Stromal Cells
    Article Snippet: .. Up to now, there are two registered clinical trials testing iMSCs, both designed by Cynata Therapeutics and using iMSCs produced by the patented CymerusTM platform technology. ..



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    Image Search Results


    Effect of XF-iMSCs-secreted EVs in mouse primary cells. XF-iMSC-secreted EVs (XF-iEv) and human adipocyte-derived MSC-secreted EVs (hAC-Ev) were purified using the MagCapture Exosome Isolation Kit. (A) Mouse peripheral blood mononuclear cells (mPBMCs; 2 × 10 6 cells/mL) were stimulated with LPS (10 ng/mL) for 24 h. Levels of IL-6, TNF-α, and IL-10 in culture supernatants were quantified by ELISA. (B) Mouse splenocytes (2 × 10 6 cells/mL) were stimulated with Dynabeads CD3/CD28 for 24 h. Levels of IL-2, IFN-γ, and IL-17 in culture supernatants were quantified by ELISA. hPBMCs were cultured with different concentrations of XF-iEv or hAC-Ev (x1, x2, x10, x50). Data are presented as mean ± SD. + p < 0.05, ++ p < 0.01, +++p < 0.001 (Aspin-Welch's t -test), # p < 0.05; ## p < 0.01; ### p < 0.001 (Dunnett test, vs control group).

    Journal: Regenerative Therapy

    Article Title: Anti-inflammatory and immunomodulatory effects of human induced pluripotent stem cells-derived mesenchymal stem/stromal cells and their extracellular vesicles

    doi: 10.1016/j.reth.2026.101081

    Figure Lengend Snippet: Effect of XF-iMSCs-secreted EVs in mouse primary cells. XF-iMSC-secreted EVs (XF-iEv) and human adipocyte-derived MSC-secreted EVs (hAC-Ev) were purified using the MagCapture Exosome Isolation Kit. (A) Mouse peripheral blood mononuclear cells (mPBMCs; 2 × 10 6 cells/mL) were stimulated with LPS (10 ng/mL) for 24 h. Levels of IL-6, TNF-α, and IL-10 in culture supernatants were quantified by ELISA. (B) Mouse splenocytes (2 × 10 6 cells/mL) were stimulated with Dynabeads CD3/CD28 for 24 h. Levels of IL-2, IFN-γ, and IL-17 in culture supernatants were quantified by ELISA. hPBMCs were cultured with different concentrations of XF-iEv or hAC-Ev (x1, x2, x10, x50). Data are presented as mean ± SD. + p < 0.05, ++ p < 0.01, +++p < 0.001 (Aspin-Welch's t -test), # p < 0.05; ## p < 0.01; ### p < 0.001 (Dunnett test, vs control group).

    Article Snippet: XF-iMSC-secreted EVs (XF-iEv) and human adipocyte-derived MSC-secreted EVs (hAC-Ev) were purified using the MagCapture Exosome Isolation Kit. (A) Mouse peripheral blood mononuclear cells (mPBMCs; 2 × 10 6 cells/mL) were stimulated with LPS (10 ng/mL) for 24 h. Levels of IL-6, TNF-α, and IL-10 in culture supernatants were quantified by ELISA. (B) Mouse splenocytes (2 × 10 6 cells/mL) were stimulated with Dynabeads CD3/CD28 for 24 h. Levels of IL-2, IFN-γ, and IL-17 in culture supernatants were quantified by ELISA. hPBMCs were cultured with different concentrations of XF-iEv or hAC-Ev (x1, x2, x10, x50).

    Techniques: Derivative Assay, Purification, Isolation, Enzyme-linked Immunosorbent Assay, Cell Culture, Control